PUBLICATIONS
"If you know you are on the right track, if you have this inner knowledge, then nobody can turn you off... no matter what they say."
- Barbara McClintock
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K.A. Greco, C.A. Franzen, K.E. Foreman, R.C. Flanigan, P.C. Kuo, G.N. Gupta. PLK-1 Silencing in Bladder Cancer by siRNA Delivered with Exosomes. Urology. Urology 2016 May: 91(241), e 1-7.
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C.A. Franzen, R. H. Blackwell, K.E. Foreman, P.C. Kuo, G.N. Gupta. Urinary Exosomes: The Potential for Biomarker Utility, Intercellular Signaling, and Therapeutics in Urologic Malignancy. Invited Review for Journal of Urology 2016 May; 195(5): 1331-9.
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C.A. Franzen, R.H. Blackwell, V. Todorovic, K.A. Greco, K. E. Foreman, R.C. Flanigan, P.C. Kuo, and G.N. Gupta. Urothelial Cells Undergo Epithelial to Mesenchymal Transition After Exposure to Muscle Invasive Bladder Cancer Exosomes. Oncogenesis 2015 Aug 17.
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J. Driver, C.E. Weber, J.J. Callaci, A. Kothari, M.A. Zapf, P.K. Roper, D. Borys, C.A. Franzen, G.N. Gupta, P.Y. Wai, J. Zhang, P.C. Kuo, Z. Mi. Alcohol Inhibits Osteopontin Dependent Transforming Growth Factor-β1 Expression in Human Mesenchymal Stem Cells. Journal of Biological Chemistry 2015 Apr 17; 290(16).
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R.H. Blackwell, C.A. Franzen, R.C. Flanigan, P.C. Kuo and G.N. Gupta. The untapped potential of urine shed bladder cancer exosomes: biomarkers, signaling, and therapeutics. Bladder 2014; 1(1)
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Z. Mi , C.Weber, P. Wai, N. Li, J. Driver, C.A. Franzen, G.N. Gupta, J. Zhang, and P.C. Kuo. Osteopontin Mediates TGF-β1 Dependent Transformation Of Mesenchymal Stem Cells Into Cancer Associated Fibroblasts In Breast Cancer Oncogene 2014 Dec 22
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C.E. Weber, J. Driver, C.A. Franzen, J.B. Mascarenhas, Z. Mi, G.N. Gupta, P.Y. Wai, and P.C. Kuo. The Constituents and Potential Targets of the Extracellular Matrix: Implications for Carcinogenesis and Cancer Treatment. Carcinogenesis and Mutagenesis 2013.
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C.A. Franzen, P.E. Simms, A.F. Van Huis, K.E. Foreman, P.C. Kuo, and G.N. Gupta. Characterization of Uptake and Internalization of Exosomes by Bladder Cancer Cells. BioMed Research International 2014.
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S. Mirzoeva, C. A. Franzen, and J. C. Pelling. Apigenin inhibits VEGF expression in human prostate carcinoma cells via a Smad- and Src-dependent mechanism. Molecular Carcinogenesis 2013.
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C.A. Franzen, V. Todorović, B.V. Desai, K.J. Green, and J.C. Pelling. The desmosomal armadillo protein plakoglogin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling PLoS One 2012 July; 7(7)
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C.A. Franzen, E. Amargo, V. Todorovic, B.V. Desai, S. Huda, S. Mirzoeva, K. Chiu, B.A. Grzybowski, T-L Chew, K.J. Green, and J.C. Pelling. The chemopreventive bioflavonoid apigenin inhibits PC3-M cell motility through the focal adhesion kinase (FAK)/Src signaling pathway. Cancer Prev Res. 2009 Sep;2(9):830-41.
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Mirzoeva S., N.D. Kim, K. Chiu, C.A. Franzen, R.C. Bergan, and J.C. Pelling. Inhibition of HIF-1 alpha and VEGF Expression by the Chemopreventive Bioflavonoid Apigenin is Accompanied by Akt Inhibition in Human Prostate Carcinoma PC3-M Cells. Mol Carcinog. 2008 Sep;47(9):686-700.
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Franzen, C.A., C.C. Chen, V. Todorović, V. Jurić, R.I. Monzon, and L.F. Lau. Integrin-Mediated Matrix Signaling Regulates TRAIL-Induced Apoptosis in Prostate Carcinoma Cells. Mol. Cancer Res. 2009 Jul; 7(7):1045-55
Publications
Abstracts
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W. Wang, C.A. Franzen, M. Sukhanova, G. Venkataraman, M. Ming, A. Guo, P. Lu, D. Sheng, A. Gao, C. Xia, J. Li, X. Zhou, and Y. L. Wang. RAC2 mediates the link between B-Cell Receptor signaling and cell adhesion in mantle cell lymphoma. Lymphoma Research Foundation Mantle Cell Lymphoma Workshop, Atlanta, 2018, Oral Presentation.
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W. Wang, C.A. Franzen, M. Sukhanova, G. Venkataraman, M. Ming, A. Guo, P. Lu, D. Sheng, A. Gao, C. Xia, J. Li, X. Zhou, and Y. L. Wang. RAC2 links B-cell receptor signaling and cell adhesion in mantle cell lymphoma. American Society for Hematology, Atlanta, 2017, Poster.
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C.A. Franzen, K.A. Greco, R.H. Blackwell, K.E. Foreman, G.N. Gupta. Urothelial cells undergo epithelial to mesenchymal transition after exposure to muscle invasive bladder cancer exosomes. American Urological Association annual meeting, New Orleans, 2015, Poster.
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A.F. Van Huis, C.A. Franzen, and G.N. Gupta. Exosome-Mediated Regulation of PTEN Expression in Bladder Cancer. American Urological Association annual meeting, Orlando, 2014, Poster.
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K.A. Greco, C.A. Franzen, P.C. Kuo, R.C. Flanigan, and G.N. Gupta. PLK1 Silencing in Bladder Cancer by siRNA Delivered with Exosomes. American Urological Association annual meeting, Orlando, 2014, Poster.
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C.A. Franzen, P. Simms, K.E. Foreman, and G.N. Gupta. Novel Method Of Exosome Quantification And Cellular Uptake Using The Amnis ImageStreamX. International Society for Extracellular Vesicles meeting, Boston, 2013, Poster.
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C.A. Franzen, V. Todorović, J.C. Pelling, R.C. Bergan. Apigenin regulates prostate cancer matrix composition, cell attachment, and cell motility through an integrin alpha 1 dependent pathway. Aspen Cancer Conference, Aspen, 2012, Poster.
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C.A. Franzen, V. Todorović, J.C. Pelling, R.C. Bergan. Apigenin regulates prostate cancer matrix composition, cell attachment, and cell motility through an integrin alpha 1 dependent pathway. American Association for Cancer Research, Chicago, 2012, Poster.
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C.A. Franzen, S. Mirzoeva, R.C. Bergan, K.J. Green, and J.C. Pelling. Apigenin inhibits PC3-M cell motility through the FAK/Src signaling pathway. Cytoskeleton Signaling in Cancer meeting, San Diego, 2008, Poster.
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C.A. Franzen, R.I. Monzon, and L.F. Lau. The extracellular matrix protein CCN1 (CYR61) sensitizes prostate carcinoma cells to TRAIL-induced apoptosis. American Association for Cancer Research, Washington D.C., 2006, Poster.